Friday, August 31, 2012

Officially accepted into Clinical Trial

I will start my new chemotherapy tomorrow - ARQ 197 (tivantinib) as part of the Clinical Trial

I'll take 360 mg of the drug twice a day with my breakfast and dinner.  The only "caution" is no grapefruit or grapefruit juice.  It's amazing how many drugs are incompatible with that healthy fruit! 

Being on this trial will require regular trips to Dana Farber - every other week after the first few weeks.  They are going to get tired of seeing me!!!  And I get to stay on the trial drug for as long as it's effective.  So we're hoping for a nice long run with very gentle side effects.  Based on the documentation and what I've read, fatigue seems to be the biggest complaint.  Less than 20% of participants have problems with low blood counts and a list of other things, nothing too daunting. 

I feel like a pioneer!  There are just 40 participants in this trial and I get to be one of them.  I think they have expanded the size of the trial because initially, it was 26 and Dana Farber had just 2 slots.  I think the clinical trial world is ever-changing. 

I am very optimistic that this drug will be effective for me and hopefully, a future treatment for all triple negative breast cancer sisters. 

Keep your fingers crossed!


  1. I'll be praying that the new pills will work for you. I am still in shock that all you went through it came back. With this pill and little side effects I hope you don't lose your beautiful hair again.

    When the Hawaii trip? Congrats on the good A1c of 6.0. You did good. Prayers to you and your family, Deb

  2. You are a pioneer! I hope this trial is successful not only for your but for so many others fighting this disease. As always, I keep you and your wonderful family in my prayers.


  3. I'm cheering you on, and I send positive energy to you when I am at my Tai Chi class.

  4. Thanks, my friends!

    Deb - no hair loss with this drug, although I admit that I'd accept hair loss for a drug that brings about remission. But luckily, this one doesn't appear to have very many side effects.

    1. Michelle I am glad to hear you'll be able to keep your beautiful hair this time. My prayers will continue that it is a complete success and you go in remission and stay there. Deb

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